Systolic ShMOLLI myocardial T1-mapping for improved robustness to partial-volume effects and applications in tachyarrhythmias

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Systolic ShMOLLI myocardial T1-mapping for improved robustness to partial-volume effects and applications in tachyarrhythmias

BACKGROUND T1-mapping using the Shortened Modified Look-Locker Inversion Recovery (ShMOLLI) technique enables non-invasive assessment of important myocardial tissue characteristics. However, tachyarrhythmia may cause mistriggering and inaccurate T1 estimation. We set out to test whether systolic T1-mapping might overcome this, and whether T1 values or data quality would be significantly differe...

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Systolic ShMOLLI T1-mapping is feasible in tachyarrhythmia, with improved image quality compared to diastolic readout

Background T1-mapping using the Shortened Modified Look-Locker Inversion Recovery (ShMOLLI) technique [1] enables assessment of myocardial characteristics, such as oedema, scar and diffuse fibrosis. However, cardiac pathology is often accompanied by tachyarrhythmia, which may cause mistriggering and inaccurate T1 estimation. We hypothesised that systolic T1-mapping may overcome this issue witho...

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Robust T1 mapping in the presence of partial volume effects

Introduction: The longitudinal relaxation time (T1) of tissues plays an important role both as a contrast mechanism for anatomical imaging and as a disease marker. To date, several techniques have been proposed for measuring it (e.g. [1,2]). Most of them are based on modeling monoexponential behavior for individual voxels. Even though brain tissue is considered to exhibit monoexponential T1 beh...

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Systolic T1 mapping for estimation of myocardial diffuse fibrosis

Background Parametric T1 mapping currently allows non-invasive estimation of diffuse left-ventricular fibrosis. Imaging for T1 mapping is usually acquired during the diastolic phase. However, in tachycardia and arrhythmia, diastasis is short and imaging challenging. Conversely, systolic T1 mapping might offer an advantage and further enable more accurate ROI delineation for T1 maps as the myoca...

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Magnetic Resonance

سال: 2015

ISSN: 1532-429X

DOI: 10.1186/s12968-015-0182-5